ALS India Life Sciences was established in 2017 with R&D and Manufacturing units. ALS is the leading manufacturer of
Active Pharmaceutical Ingredients (APIs), Intermediates, Advance Intermediates, Specific Pharmaceutical Intermediates, Speciality Chemicals, Impurities, Pharma reagents and Key Starting Materials (KSMs). Apart from this, we also focus on high-end contract research, process development, custom synthesis, custom synthesis of complex molecules,
Contract Research and Manufacturing Services (CRAMs), Drug Discovery and Development Support Services (DDDSS) and difficult to manufacture intermediates and APIs. We have a capability to synthesize in Mg to multi-kg scale.
ALS India Life Sciences is a leading
Contract Development and Manufacturing Organisation (CDMO) for small molecules, APIs and Intermediates. We offer a wide range of services to innovators from development to commercialization.
ALS India Life Sciences has a Highly skilled and diverse team comprising of PhD’s, post graduates and chemical engineers. Our R&D team offers co-development of novel molecules for pharmaceutical advancement. We possess extensive experience in optimizing processes for development of safe and environment friendly commercial production. Our expertise includes:
- High pressure reaction with Pd/Ru/Rd etc.,
- Ligands such as Pd(OAc)2, Pd2(dba)3.DCM, Pd(PPh3)4, Pd(PPh3)2Cl2
- RuPhos, SPhos, X-Phos and xantphos
- Cyanation,
- Electro-chemical reactions,
- Bromination/Chlorination,
- Asymmetric synthesis,
- Cryogenic reactions,
- Butyl lithium reactions,
- Grignard reaction,
- Oxidation and Reduction reactions,
- Reductive Amination
- Pressure reactions,
- Enzymatic reactions,
- Steroid chemistry,
- Pyrimidine chemistry,
- Pyridine chemistry,
- Purine chemistry,
- Nucleoside chemistry,
- Indole chemistry,
- Cyclopropane/ Cyclobutane chemistry,
- Boron chemistry,
- Phase transfer catalyst,
- Hydrogenation including asymmetric capabilities,
- Hydrogenation multi-step complex chemistry,
- Extended coupling reactions,
- Nucleoside & Carbohydrate chemistry,
- Asymmetric catalysis,
- Organometallics,
- Buchwald-Hartwig Cross Coupling Reaction
- Gilman reaction
- Heck–Matsuda coupling reaction
- Negishi Coupling
- Stille coupling reactions
- Suzuki–Miyaura reaction
- Tsuji-Trost Reaction
- Ullmann Reaction
- Carbonylations using carbon monoxide on multi kilo scale
- Chiral Synthesis including the development of suitable analytical chiral methods.
- Chiral separations
Our Capability to handling and developing cytotoxic intermediates/APIs. Our capability to carry out full-scale patent evaluation including development of non-infringing processes & collaborative programs under confidentiality agreement.